Toxicologists Brace for Genomics Revolution

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Science  28 Jul 2000:
Vol. 289, Issue 5479, pp. 536-537
DOI: 10.1126/science.289.5479.536

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ASPEN, COLORADO-- According to researchers who gathered here at a high-powered summit this month, toxicology may be on the verge of changing the way it collects raw data--adopting a process that could reduce animal use and improve test results. The new approach, called "toxicogenomics," uses DNA arrays to profile gene expression in cells exposed to test compounds. But some leaders in the field warn against rushing too quickly to embrace DNA tests, which are still difficult to interpret.

  • *26th Annual Summer Meeting, The Toxicology Forum, 10 to 14 July.