PerspectiveBiochemistry

All in the Ubiquitin Family

Science  28 Jul 2000:
Vol. 289, Issue 5479, pp. 563-564
DOI: 10.1126/science.289.5479.563

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Summary

The job of a protein can be altered by addition of molecules such as ubiquitin or the related ubiquitin-like modifiers, which bring about changes in the protein's localization, conformation, or its interactions with other proteins. In a comprehensive Perspective, Hochstrasser brings us up to date with the many new members of the ubiquitin modifier family and their multitudinous and diverse protein targets.

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