News of the WeekNeurobiology

Long-Sought Protein Packages Glutamate

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Science  11 Aug 2000:
Vol. 289, Issue 5481, pp. 847-849
DOI: 10.1126/science.289.5481.847a

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Glutamate, one of two neurotransmitters that send the basic "stop" and "go" signals that most other neurotransmitters merely modulate, is called into action wherever rapid-fire excitatory signals are needed--say, for vision or learning. For decades, researchers have been looking for the protein that packages glutamate for express delivery to other neurons. On page 957, researchers report that they've found this elusive transporter, dubbed VGLUT1.