Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

Simon Melov; Joanne Ravenscroft; Sarwatt Malik; Matt S. Gill; David W. Walker; Peter E. Clayton; Douglas C. Wallace; Bernard Malfroy; Susan R. Doctrow; Gordon J. Lithgow

doi:10.1126/science.289.5484.1567

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Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

Simon Melov1,
Joanne Ravenscroft2,*,
Sarwatt Malik2,
Matt S. Gill2,
David W. Walker2,†,
Peter E. Clayton2,
Douglas C. Wallace3,
Bernard Malfroy4,
Susan R. Doctrow4,
Gordon J. Lithgow2,‡

¹ Buck Institute for Age Research, Novato, CA 94949, USA.
² The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.
³ Center for Molecular Medicine, Emory University, Atlanta, GA 30322, USA.
⁴ Eukarion, Bedford, MA 01730, USA.

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Science 01 Sep 2000:
Vol. 289, Issue 5484, pp. 1567-1569
DOI: 10.1126/science.289.5484.1567

Simon Melov

Buck Institute for Age Research, Novato, CA 94949, USA.

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Joanne Ravenscroft

The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.

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Sarwatt Malik

The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.

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Matt S. Gill

The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.

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David W. Walker

The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.

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Peter E. Clayton

The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.

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Douglas C. Wallace

Center for Molecular Medicine, Emory University, Atlanta, GA 30322, USA.

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Bernard Malfroy

Eukarion, Bedford, MA 01730, USA.

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Susan R. Doctrow

Eukarion, Bedford, MA 01730, USA.

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Gordon J. Lithgow

The School of Biological Sciences and the Academic Unit of Child Health, The University of Manchester, Manchester, M13 9PT, UK.

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Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

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