Twist and Fluoresce

Science  13 Oct 2000:
Vol. 290, Issue 5490, pp. 286-287
DOI: 10.1126/science.290.5490.286

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Catalytic antibodies, or artificial enzymes, act as catalysts by lowering the energy of the transition state of a reaction. In his Perspective, Brauman highlights the study by Simeonov et al., who have applied similar principles to photochemical processes and shown that intense fluorescence can be achieved. The approach provides a way of measuring internal molecular motion within the antibody on a very fast time scale. Fluorescent antibodies may find applications in immunochemistry, histological assays, and genomic studies.