News of the WeekPHYSIOLOGY NOBEL

Celebrating the Synapse

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Science  20 Oct 2000:
Vol. 290, Issue 5491, pp. 424
DOI: 10.1126/science.290.5491.424a

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Summary

Last week, the Nobel Assembly awarded the Nobel Prize in physiology or medicine to Arvid Carlsson of the University of Gothenburg in Sweden, who discovered that dopamine is a key neurotransmitter in the brain, and to two other pioneers in the study of nerve cell communications: Paul Greengard of Rockefeller University in New York City, who figured out how dopamine and other neurotransmitters trigger their target neurons when they bind at the synapse, the junction between two nerve cells; and Eric Kandel of New York's Columbia University, who built on these insights to demystify some aspects of learning and memory.