Translational Roots for Mental Retardation?

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Science  27 Oct 2000:
Vol. 290, Issue 5492, pp. 737
DOI: 10.1126/science.290.5492.737

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A flurry of findings points to protein translation in the dendrites of neurons as a key feature leading to the changes at synapses that are vital to learning (see main text). And one recent discovery suggests that when this translation goes awry, it can lead to mental retardation.