Varied Fates from Similar States

Science  03 Nov 2000:
Vol. 290, Issue 5493, pp. 944
DOI: 10.1126/science.290.5493.944a

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Chance, Development, and Aging. Caleb E. Finch and Thomas B. L. Kirkwood. Oxford University Press, New York, 2000. 288 pp. $35, £24.95. ISBN 0-19-513361-7.

Finch and Kirkwood draw on research in developmental biology to argue that random variations in cell fate and function modify genetic and external environmental influences to determine the course of aging in individuals.