Contents

22 December 2000
Vol 290, Issue 5500

About The Cover

Cover image expansion

COVER Creatures great and small are having their genomes sequenced, as highlighted in this Breakthrough of the Year special issue. Now that genomics has come of age, the growing library of gene sequence data is opening a new era of sophisticated genetics research. See the Breakthrough of the Year special section, beginning on page 2220, and the Editorial on page 2255. [Illustration: Peter Steiner]