Boosting Working Memory

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Science  22 Dec 2000:
Vol. 290, Issue 5500, pp. 2275-2276
DOI: 10.1126/science.290.5500.2275

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Working out which areas of the brain become activated during the formation of working (short-term) memory has been greatly helped by functional magnetic resonance imaging (fMRI). In a Perspective, Robbins et al. discuss new findings ( Furey et al. ) with fMRI that reveal how working memory is enhanced by the drug physostigmine, which increases cholinergic function in the brain.