RESOURCES: Proteins in 31 Flavors

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Science  05 Jan 2001:
Vol. 291, Issue 5501, pp. 19
DOI: 10.1126/science.10.1126/SCIENCE.291.5501.19C

Contrary to appearances, people and slime molds have a lot in common: around 1000 genes. That explains why biologists trying to decipher a gene's function will look for similar genes and the proteins they code for in other species. Toward that end, the European Bioinformatics Institute, U.K., has just released results from a massive exercise that compared what's known about 31 sequenced genomes (including many microbes and the fruit fly). Using a program called GeneQuiz that runs on supercomputers to crunch data from public databases, the group predicted functions for more than 40,000 of 73,500 surveyed genes—15% more than had originally been reported. Generate a report on your favorite gene by following the links at

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