News of the WeekGenome Research

Progress for the 'Mouse Gene Encyclopedia'

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Science  09 Feb 2001:
Vol. 291, Issue 5506, pp. 963-964
DOI: 10.1126/science.291.5506.963a

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Summary

TOKYO-- It's not enough simply to sequence the genome of an organism; it's also necessary to identify the genes and determine what they do. An international consortium has now provided the first installment of what promises to be a key resource for filling this gap for the soon-to-be-published human genome. In this week's issue of Nature, the researchers report that they have produced full-length complementary DNA (cDNA) clones of nearly 13,000 mouse genes-about 20% of the total. Because many of the mouse and human genes are likely to be similar, these cDNAs will help researchers identify genes within the human genome sequence as well as that of the mouse when it becomes available.