Introduction to special issueTHE HUMAN GENOME

Science Genome Map

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Science  16 Feb 2001:
Vol. 291, Issue 5507, pp. 1218
DOI: 10.1126/science.291.5507.1218

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Two groups have been using different strategies to complete the sequencing of the human genome. Both have now reached goals that were set--the publicly funded effort to produce a working draft of the human genome by a map-based strategy and Celera, to sequence the human genome by the whole-genome shotgun approach. The availability of sequence material obtained through different approaches greatly facilitates the ability of the entire scientific community to interpret the data. This chart provides an introduction to these efforts and some of the revolutionary questions that can be approached with the human genome sequence as a tool.