News of the WeekAIDS VACCINES

Long-Lasting Immunity Conferred in Monkeys

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Science  09 Mar 2001:
Vol. 291, Issue 5510, pp. 1879-1881
DOI: 10.1126/science.291.5510.1879b

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In a paper published online today by Science (, researchers describe a two-step AIDS vaccine strategy they developed using a laboratory-made, hybrid virus called SHIV (which is part HIV and part SIV, a simian AIDS virus) and modified vaccinia Ankara, a version of the virus used as the smallpox vaccine. In a large monkey experiment, this vaccine appears to have stimulated long-lasting immunity.