News FocusCOMPARATIVE GENOMICS

Gene Expression Differs in Human and Chimp Brains

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Science  06 Apr 2001:
Vol. 292, Issue 5514, pp. 44-45
DOI: 10.1126/science.292.5514.44

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Summary

TOKYO-- Genetic variation may explain why humans differ from their primate cousins, but not in the way one might expect. Although the human genome differs only slightly--an estimated 1% to 2%--from those of the great apes, there are significant differences in how genes are expressed and regulated. New research reported at a meeting here last month suggests that those differences are most marked in the brain, a finding that offers possible clues to how humans developed their prodigious mental capacity.