PerspectiveMolecular Biology

Invading the Genetic Code

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Science  20 Apr 2001:
Vol. 292, Issue 5516, pp. 453-454
DOI: 10.1126/science.1060637

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All organisms, regardless of where they live or what they do, have but 20 amino acids. This dogma may be about to change, according to Böck in a Perspective. He discusses new results ( Wang et al., Doring et al.) describing strategies for supplementing the amino acid repertoire of bacteria with unnatural amino acids, which could be applied to the engineering of completely new proteins.