TOOLS: Get Your SNPset

See allHide authors and affiliations

Science  18 May 2001:
Vol. 292, Issue 5520, pp. 1267
DOI: 10.1126/science.292.5520.1267c

Informatics experts at Harvard's Children's Hospital have developed a Web tool that makes it a breeze to troll public databases for SNPs, single-nucleotide mutations used as markers for finding disease genes. SNPper, as it's called, looks for SNPs in major databases and puts them “in a format that is easy to use,” says Harvard's Alberto Riva. Users can search by position on the chromosome or by gene name and receive all the SNPs in that region. They can then view the SNPs in the gene sequence or download their SNPset into other computer programs, for example to design PCR primers (used for making copies of DNA).

Navigate This Article