Cracking Listeria's Password

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Science  01 Jun 2001:
Vol. 292, Issue 5522, pp. 1665-1667
DOI: 10.1126/science.1062045

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Listeriosis is a serious food-borne bacterial disease that causes death in newborns and the elderly and can induce late-term miscarriages in pregnant women. In a Perspective, Finlay discusses a new mouse model of listeriosis ( Lecuit et al.) that mimics the oral infection route of humans and confirms the part played by the bacterial surface protein, internalin, in enabling the bacteria to enter gut epithelial cells of the host.