PerspectiveStructural Biology

A Marvellous Machine for Making Messages

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Science  08 Jun 2001:
Vol. 292, Issue 5523, pp. 1844-1846
DOI: 10.1126/science.1062384

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The wonderful x-ray structures of RNA polymerase published in the past 3 years have revealed a wealth of information about how genes are transcribed. In an eloquent Perspective, Klug describes the latest tour de force from Kornberg's laboratory: the crystal structure of yeast RNA polymerase II in action.