PerspectiveCell Biology

A Switch to Release the Motor

Science  17 Aug 2001:
Vol. 293, Issue 5533, pp. 1263-1264
DOI: 10.1126/science.1064602

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Most organelle transport ceases when cells begin mitosis. But how is this accomplished? As Cheney and Rodriguez explain in their Perspective, cell cycle-dependent phosphorylation of myosin-V--a motor protein that moves organelles along actin filaments--results in release of myosin-V from the organelle and cessation of actin-based organelle transport ( Karcher et al.).