PerspectiveBiochemistry

TRP Ion Channels--Two Proteins in One

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Science  17 Aug 2001:
Vol. 293, Issue 5533, pp. 1270-1271
DOI: 10.1126/science.1062504

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Summary

It is well established that some proteins carry out more than one job in the cell, but so far, ion channels do not appear to exhibit this versatility. In their Perspective, Levitan and Cibulsky discuss a cluster of new findings showing that two members of the long TRP ion channel family, LTRPC7 and LTRPC2, are both ion channels and enzymes.