News of the WeekGenetics

Closing In on the Centromere

See allHide authors and affiliations

Science  05 Oct 2001:
Vol. 294, Issue 5540, pp. 30-31
DOI: 10.1126/science.294.5540.30

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

On page 109, geneticists provide the clearest look yet at a human centromere, the cinched waist of a chromosome. They have demonstrated that a 3-million-base stretch of DNA embedded in what many have called the centromere is really all it takes to make a functional centromere. To their surprise, the nature of this core DNA indicates that, rather than being highly conserved, the centromere has changed significantly during primate evolution.