LINKS: A Heaping Serving of Gene Chips, Please

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Science  19 Oct 2001:
Vol. 294, Issue 5542, pp. 483
DOI: 10.1126/science.294.5542.483c

Microarrays for comparing patterns of gene expression are the hottest thing in biology and medicine since the advent of the polymerase chain reaction a decade ago. Whether you're a microarray maven or just want to know what all the fuss is about, try this diverse collection of annotated links corralled by grad student Y. F. Leung of the Chinese University of Hong Kong. Novices keen to learn the basics of gene chips might want to start with the background section, which offers several lucid, illustrated primers. Seasoned pros will find links to a range of products for making and scanning microarrays, plenty of lab protocols, and rosters of labs and people using microarray technology. The site also offers links to a dozen databases of gene expression results, such as Harvard's ExpressDB database of yeast and Escherichia coli RNA expression values. Leung has also written a handy comparison of software packages for analyzing microarray results. And if your experiment keeps bombing, a page on troubleshooting illustrates and diagnoses some common stumbling blocks.∼b400559/array.html

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