News FocusNOBEL PRIZE IN PHYSIOLOGY OR MEDICINE

Cycling Toward Stockholm

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Science  19 Oct 2001:
Vol. 294, Issue 5542, pp. 502-503
DOI: 10.1126/science.294.5542.502

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Summary

LONDON-- Paul Nurse, Tim Hunt, and Leland Hartwell have been awarded this year's Nobel Prize in physiology or medicine for identifying the key molecular steps in the cell cycle. The winners' work led to the revelation that the cell cycle is controlled through the cooperative action of two sets of proteins: the cyclins and enzymes called kinases. Their discoveries not only illuminated cell biology's most fundamental process-the ability to grow and divide-but also have had important implications for medicine.