PerspectiveImmunology

Chip Shots--Will Functional Genomics Get Functional?

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Science  26 Oct 2001:
Vol. 294, Issue 5543, pp. 799-801
DOI: 10.1126/science.1066314

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Summary

Dendritic cells are the frontline defense against invading microbial pathogens. But do they respond to a virus in the same way that they respond to a bacterium or a yeast? As Modlin and Bloom explain in their Perspective, gene expression profiling of human dendritic cells reveals that unique subsets of genes are activated in response to different pathogens ( Huang et al.).