Neurocreationism--Making New Cortical Maps

See allHide authors and affiliations

Science  02 Nov 2001:
Vol. 294, Issue 5544, pp. 1011-1012
DOI: 10.1126/science.294.5544.1011

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


In developing mammals, how does the cerebral cortex become compartmentalized into different regions responsible for functions as diverse as motor control and sensory perception? Rakic explains in his Perspective that morphogenetic molecules such as FGF8 (Fukuchi-Shimogori and Grove) form gradients that specify the boundaries of different cortical regions, which are then further modified by input from the thalamus and other cerebral structures.