News of the WeekGenetics

Fragile X's Missing Partners Identified

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Science  30 Nov 2001:
Vol. 294, Issue 5548, pp. 1809
DOI: 10.1126/science.294.5548.1809

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People with fragile X syndrome, one of the most common causes of mental retardation, carry a mutated version of a gene on the X chromosome that blocks the production of a certain protein. But how that deficit causes the syndrome remains mysterious. Now three new studies could help explain the role certain fragile X-related proteins play in the brain.