Caveolin-3 Helps Build Muscles

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Science  30 Nov 2001:
Vol. 294, Issue 5548, pp. 1864
DOI: 10.1126/science.294.5548.1864

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The cell-membrane structures called caveolae and their associated proteins--the caveolins--play a role not only in transporting materials and signals into cells (see main text) but in building the body's muscle cells. Indeed, defects in muscle caveolin have been linked to a rare form of muscular dystrophy.