PerspectivePhysiology

A One-Domain Voltage-Gated Sodium Channel in Bacteria

Science  14 Dec 2001:
Vol. 294, Issue 5550, pp. 2306-2308
DOI: 10.1126/science.1067417

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Summary

Voltage-gated sodium channels are a feature of excitable mammalian cells such as neurons, but have never been found in bacteria. In his Perspective, Catterall discusses the discovery of the first bacterial voltage-gated sodium channel ( Ren et al.) and compares the structure and function of this channel with its mammalian counterpart.

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