Review

Bayesian Inference of Phylogeny and Its Impact on Evolutionary Biology

Science  14 Dec 2001:
Vol. 294, Issue 5550, pp. 2310-2314
DOI: 10.1126/science.1065889

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Abstract

As a discipline, phylogenetics is becoming transformed by a flood of molecular data. These data allow broad questions to be asked about the history of life, but also present difficult statistical and computational problems. Bayesian inference of phylogeny brings a new perspective to a number of outstanding issues in evolutionary biology, including the analysis of large phylogenetic trees and complex evolutionary models and the detection of the footprint of natural selection in DNA sequences.

  • * To whom correspondence should be addressed. E-mail: johnh{at}brahms.biology.rochester.edu

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