News FocusMolecular Evolution

Genome Duplications: The Stuff of Evolution?

Science  21 Dec 2001:
Vol. 294, Issue 5551, pp. 2458-2460
DOI: 10.1126/science.294.5551.2458

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The controversial--and formerly unprovable--proposition that evolution moves forward through duplication of entire genomes is getting support from current advances in molecular biology. The emerging data have not persuaded all of the skeptics, however. They maintain that evolutionary change could have been fueled by duplication of individual genes or perhaps segments of chromosomes--without invoking anything as dramatic as genome duplications.