News of the WeekSTEM CELL RESEARCH

Rat Brains Respond to Embryonic Stem Cells

Science  11 Jan 2002:
Vol. 295, Issue 5553, pp. 254-255
DOI: 10.1126/science.295.5553.254b

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Summary

In a paper published online on 8 January by the Proceedings of the National Academy of Sciences, a team of neuroscientists reports that mouse embryonic stem (ES) cells can become dopamine-producing neurons in the brains of rats. These experiments are the first to show that the specific type of neurons missing in Parkinson's disease can develop from an ES cell in an animal's brain and lead to partial recovery. But several rats developed deadly tumors, and the animals' behavioral improvements were limited.

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