Integrating Interactomes

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Science  11 Jan 2002:
Vol. 295, Issue 5553, pp. 284-287
DOI: 10.1126/science.1068664

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In the postgenomic era, working out which proteins interact with each other will be important for finding out what each protein does. In their Perspective, Gerstein et al. describe new work ( Tong et al.) that combines two completely different data sets to work out which yeast proteins interact and which peptide recognition domains are involved.