The Key to Successful Organic Synthesis Is...

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Science  11 Jan 2002:
Vol. 295, Issue 5553, pp. 289-290
DOI: 10.1126/science.1068158

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Selective carbon-carbon bond formation plays a key role in organic synthesis. Existing methods are not perfect, however, and elaborate synthesis routes may be needed for a seemingly simple addition. In his Perspective, Jones highlights the report by Cho et al., who describe an important new route to carbon-carbon bond formation between unsaturated carbon centers. The reactions are quite general and selective and are likely to find widespread application in organic synthesis.