PerspectiveCell Biology

Slick Recruitment to the Golgi

Science  11 Jan 2002:
Vol. 295, Issue 5553, pp. 290-291
DOI: 10.1126/science.1068446

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Formation of vesicles carrying secretory proteins depends on the activity of the Golgi, the cell's central protein sorting station. In a Perspective, Bankaitis discusses new findings (Baron and Malhotra) that reveal how protein kinase D, a key molecule required for vesicle formation, is recruited to the Golgi by a lipid called diacylglycerol that is both produced and consumed within this organelle.