PerspectiveCELL CYCLE

A Trigger for Centrosome Duplication

Science  18 Jan 2002:
Vol. 295, Issue 5554, pp. 455-456
DOI: 10.1126/science.1068917

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Duplication of the centrosome is a crucial event that must take place if cell division is to proceed normally. In a Perspective, Arlot-Bonnemains and Prigent discuss new work (Matsumoto and Maller) that identifies CaMKII as the trigger for centrosome duplication during S phase.