News FocusCell Biology

Cell Migration Research Is on the Move

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Science  25 Jan 2002:
Vol. 295, Issue 5555, pp. 606-609
DOI: 10.1126/science.295.5555.606

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One of cell biology's first mysteries, cell motility is finally emerging as a unified field as new techniques allow researchers to follow in cells' steps. Stripped-down model systems and methods to search for migration-related genes and proteins on a large scale are enabling researchers to identify the multiplicity of players and track their interactions. Techniques to monitor and manipulate mechanical forces in living cells are providing clearer views of the dynamics of cell movement. And computer models are helping researchers design experiments, test hypotheses, and integrate the wealth of data.