Chaperones Take Flight

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Science  01 Feb 2002:
Vol. 295, Issue 5556, pp. 809-810
DOI: 10.1126/science.1069544

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The fruit fly is turning out to be a valuable model of human neurodegenerative diseases such as Parkinson's disease (PD) and a useful tool for screening potential therapeutics for treating these illnesses. In his Perspective, Helfand discusses a new fly model of PD in which the loss of dopaminergic neurons is prevented by expression of chaperone proteins ( Auluck et al.).