PerspectiveNeurobiology

What the Synapse Tells the Neuron

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Science  08 Mar 2002:
Vol. 295, Issue 5561, pp. 1845-1846
DOI: 10.1126/science.1070513

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Summary

How do neurons integrate the thousands of synaptic inputs to their dendrites that arrive from other nerve cells? In his Perspective, Mel discusses new findings in the pyramidal neurons of rat brain that show how synaptic responses vary depending on their site of origin in the dendritic tree and how tiny signals from far out in the dendrites can be boosted so that the cell body receives a large signal (Williams and Stuart).

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