A Tail of Two Specifi-cities

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Science  15 Mar 2002:
Vol. 295, Issue 5562, pp. 2031-2032
DOI: 10.1126/science.1070586

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The pathogenic bacterium Bordetella can switch phenotype to evade attack by viruses called bacteriophages. In his Perspective, Hatfull discusses new work ( Liu et al .) that describes how a bacteriophage uses a reverse transcriptase-dependent process to generate variants that can infect both phenotypes of Bordetella.