PerspectiveVirology

Rafting with Ebola

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Science  12 Apr 2002:
Vol. 296, Issue 5566, pp. 279
DOI: 10.1126/science.1070868

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Summary

Lipid rafts are microdomains in the cell plasma membrane that are enriched in cholesterol, saturated fatty acids, and certain proteins. In a Perspective, Freed discusses new work published elsewhere showing that filoviruses, including the deadly human pathogens Ebola and Marburg, use these lipid rafts to infect host cells and to assemble new virus particles.

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