News FocusImmunology

Gently Soothing a Savage Immune System

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Science  19 Apr 2002:
Vol. 296, Issue 5567, pp. 456-458
DOI: 10.1126/science.296.5567.456

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Autoimmune disease and transplant researchers are teaming up in their search for ways to make the immune system tolerate tissue it's attacking. The new approach, called immune tolerance as opposed to immune suppression, is driven by work in the transplant field, but experts in autoimmune diseases are also getting into the game--in their case to modulate attacks on the patient's own tissue. Results from animal studies have generated promising findings, and dozens of clinical trials are now under way or gearing up.