News of the WeekALCOHOLISM RESEARCH

Stressed Mutant Mice Hit the Bottle

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Science  03 May 2002:
Vol. 296, Issue 5569, pp. 823-824
DOI: 10.1126/science.296.5569.823a

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Summary

Some people can drink moderately for years, only to become mired in alcohol after a stressful life event. A new mouse model described on page 931 may help explain why. In the mice, which have been genetically altered to lack a key component of their stress response system, stress apparently acts as a catalyst that makes them--perhaps permanently--more prone to drink.