Special Reviews

Germline Stem Cell Transplantation and Transgenesis

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Science  21 Jun 2002:
Vol. 296, Issue 5576, pp. 2174-2176
DOI: 10.1126/science.1071607

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The recently developed testis cell transplantation method provides a powerful approach to studying the biology of the male germline stem cell and its microenvironment, the stem cell niche. The technique also is being used to examine spermatogenic defects, correct male infertility, and generate transgenic animals.

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