TOOLS: A Cut Above

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Science  12 Jul 2002:
Vol. 297, Issue 5579, pp. 163
DOI: 10.1126/science.297.5579.163b

Restriction enzymes are molecular shears that sever DNA strands at a particular sequence of bases. Molecular biologists can find out where a certain enzyme will slice a specific length of DNA by using RestrictionMapper. Enter a DNA sequence and choose from among a list of several hundred commercially available restriction enzymes. The program tells you which enzymes will snip the strand and where, and then it supplies the sequences of the fragments. Also check out the links to other free molecular biology software, including programs for sequence alignment and gene annotation.

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