News of the WeekEMBRYONIC STEM CELLS

Stem Cells Not So Stealthy After All

Science  12 Jul 2002:
Vol. 297, Issue 5579, pp. 175-177
DOI: 10.1126/science.297.5579.175a

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Summary

As human embryonic stem (ES) cells differentiate, they express increasing levels of the telltale tags the body uses to distinguish between native and foreign cells. The findings, published online this week by the Proceedings of the National Academy of Sciences, confirm that a patient's immune system would be likely to reject transplanted tissues derived from ES cells. Scientists will therefore have to find ways to reconcile the body's defense system with the transplanted cells.

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