PerspectiveDevelopment

Riding the Crest of the Wnt Signaling Wave

+ See all authors and affiliations

Science  02 Aug 2002:
Vol. 297, Issue 5582, pp. 781-783
DOI: 10.1126/science.1075454

You are currently viewing the summary.

View Full Text

Summary

Formation of the neural crest is a crucial step during the embryonic development of vertebrates, but the signals that direct neural crest induction are largely unknown. In their Perspective, Trainor and Krumlauf discuss new findings ( García-Castro et al.) revealing that Wnt6 expression in the surface ectoderm directs neural crest induction.