Vertebrate Genomes Compared

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Science  23 Aug 2002:
Vol. 297, Issue 5585, pp. 1283-1285
DOI: 10.1126/science.1076231

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The complete genome sequence of the tiger pufferfish Fugu ( Aparicio et al. ) should enable valuable comparisons to be made with the human genome. In a Perspective, Hedges and Kumar discuss how the Fugu genome sheds light on the genetics of human disease and on the evolutionary relationships of vertebrates.