Science  30 Aug 2002:
Vol. 297, Issue 5586, pp. 1451a
DOI: 10.1126/science.297.5586.1451a

Like a balky photocopier, the cellular machinery that makes proteins sometimes jams partway through a job. Many bacteria respond by summoning their own version of the copier technician: a molecule called tmRNA. The handy molecule clears the blockage and caps the aborted protein, flagging it for destruction by cleanup enzymes. Find out more at The tmRNA Website, curated by molecular biologist Kelly Williams of Indiana University, Bloomington. For 250 species of bugs, the site supplies tmRNA's sequences and the predicted order of amino acids in the cap. Another feature allows you to compare sequences for various combinations of species.∼tmrna

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