News of the WeekPAIN RESEARCH

Enzyme Might Relieve Research Headache

See allHide authors and affiliations

Science  20 Sep 2002:
Vol. 297, Issue 5589, pp. 1976
DOI: 10.1126/science.297.5589.1976a

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

How the popular pain reliever acetaminophen works has been largely a mystery. Now a group of biochemists has discovered in dogs a new variant of the well-studied cyclooxygenase (COX) enzyme. The newfound enzyme, dubbed COX-3, fits the profile of the long-sought site of action for the drug, which is the active ingredient in Tylenol.